How Enzymes Direct ‘Traffic’ Inside Cells
Todd Bates, 14 Nov 17
       

(Credit: Getty Images)

Protein “motors” inside cells act like trucks on tiny cellular highways to deliver life-sustaining cargo. Researchers now know how cells deploy enzymes to place traffic control and “roadway under construction” signs along those highways.

The findings could lead to new therapies for spinal cord and nerve injuries and neurodegenerative diseases.

“To stay alive and function, every cell in our body needs to transport cargoes to the place they’re needed inside the cell, in the right amount, and at the right time,” says Robert O’Hagan, assistant research professor of genetics at Rutgers University-New Brunswick and the Human Genetics Institute of New Jersey. “So there has to be a lot of organization in how transport inside the cell is regulated, and now we know a lot more about how that happens.”

The highways inside cells are called microtubules. Proteins called kinesins and dyneins act like motors—and are essentially the cargo trucks in cells. The motor proteins drive cargo around microtubule highways.

A central question in cell biology is how intracellular transport and the highway systems are organized. How do the motor proteins know where to go and how fast they need to be?

Sign in to view full article

       
Your Next Social Network Could Pay You For Posting
You may well have found this article through Facebook. An algorithm programmed by one of the world’s biggest companies now ...
Jelena Dzakula
Wed, 1 Feb 17
The Price of Connection: ‘Surveillance Capitalism’
Imagine, if you can, a period long before today’s internet-based connectivity. Imagine that, in that distant time, the populations of ...
Nick Couldry
Mon, 27 Feb 17
Norway’s Oil Fund Is A Tarnished Gold Standard For Sustainable Investment
The largest sovereign wealth fund in the world, Norway’s US$930 billion Government Pension Fund Global, is seen as the epitome ...
Beate Sjåfjell
Thu, 4 May 17
Exploring the Complexities of Forgiveness
Friday, Jan. 27 is International Holocaust Remembrance Day – an annual day that honors the memories of the victims of ...
Yerachmiel Gorelik
Tue, 31 Jan 17
Sustainable Shopping: For Eco-Friendly Jeans, Stop Washing Them So Often
Denim jeans – whether ripped, straight, flared, vintage or raw – are one of the world’s most-loved garments. But from ...
Alice Payne, Susannah Kate Devitt
Thu, 1 Jun 17
Get your January/February 2018 issue at Kinokuniya stores today!
An Epoch Times Survey
Advertise with Us
Read about Forced Organ Harvesting
Sports Elements
Sports Elements